Kif1c anthrax

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August undefined, 2024

WebAnthrax toxin is the dominant virulence factor of Bacillus anthracis and drugs blocking its action could therefore have therapeutic benefit. Three recent papers suggest new ways to inhibit the toxin. Identification of the cell surface toxin receptor could lead to the design of binding competitors and receptor decoys. Determination of the crystal structure of the … WebKIF1C Antibody. NBP1-85978. Species: Hu. Applications: WB, IHC, IHC-P. Publications using NBP1-85978. Applications. Species. Kobayakawa M, Matsubara T, Mizokami A et …

Kif1c kinesin family member 1C [ (house mouse)] - National Center …

WebThis suggested that the sensitivity to LT in the originally established Kif1c knockout mice was not due to the loss of the Kif1c gene, but was because of the presence of the … Web8 mrt. 2024 · Deze cel was vervolgens niet langer gevoelig voor de bacterie.” Bij een omgekeerd experiment beschadigden de onderzoekers het mutante Kif1C-gen in een … boufos beach crete

The Role of NF-κB and H3K27me3 Demethylase, Jmjd3, on the …

WebKIF1C is a new member of the kinesin superfamily of proteins (KIFs), which act as microtubule-based molecular motors involved in intracellular transport. WebAnthrax toxin is the dominant virulence factor of Bacillus anthracis and drugs blocking its action could therefore have therapeutic benefit. Three recent papers suggest new ways … Web14 okt. 2005 · Moreover, KIF1C has been implicated in the susceptibility of mouse macrophages to anthrax lethal toxin [ 10 ]. The other member of the Kinesin-3 family, KIF1B, is expressed as two main splicing variants that share 660 amino-terminal amino acids and have different roles in intracellular transport. boufrog

Exclusion of Kif1c as a candidate gene for anthrax toxin …

WebResults and Discussion The BMP-4 precursor undergoes ordered cleavage at two sites within the prodomain. Our previous studies on proteolytic activation of BMP-4 suggested that proBMP-4 may be cleaved at more than one site within the prodomain (Cui et al. 1998).To test this possibility, [35 S]proBMP-4 was incubated with 5 nm of recombinant furin in vitro … WebBy comparative analysis of BAC clones containing Ltxs1, the mouse locus on chromosome 11 that controls LeTx susceptibility, Watters et al. (2001) identified polymorphisms … boufroukhWebSeptische anthrax; Een van bovengenoemde vormen in combinatie met. Aantonen van Bacillus anthracis in patiëntenmateriaal. Als zich in een instelling een of meerdere gevallen met klachten en symptomen passend bij de ziekteverwekker uit deze richtlijn voordoen, kan er sprake zijn van meldingsplicht op basis van Artikel 26 Wet publieke gezondheid. boufroura

"WebAntibodies that detect KIF1C can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation and Immunocytochemistry. … " - Kif1c anthrax

Kif1c anthrax

Quickening the pace of anthrax research: three advances point …

WebTyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers … Web8 sep. 2015 · Objectives Commercial curcumin (CU), derived from food spice turmeric (TU), has been widely studied as a potential therapeutic for a variety of oncological and inflammatory conditions. Lack of...

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WebAnthrax inhalation and lethal human infection. Sir--Powders containing anthrax spores have been sent through the US mail. Inhalation has led to several deaths among … WebSi les spores de Bacillus anthracis sont inhalées, les signes initiaux de la maladie ressemblent habituellement à ceux d'un rhume (fièvre, mal de gorge, sensation générale de malaise, courbatures, fatigue, toux et inconfort au niveau de la poitrine). Les symptômes peuvent s'aggraver et mener à des troubles respiratoires sévères et à l'état de choc.

Webon the Anthrax Lethal Toxin Tolerance of RAW 264.7 Cells Nando Dulal Das, Kyoung Hwa Jung, Young Gyu Chai* Division of Molecular and Life Science, Hanyang University, … Web2 okt. 2001 · We show that Kif1C is the only gene in the Ltxs1 critical interval that contains mutations between susceptible and resistant inbred strains. Treatments that alter the …

WebAbout KIF1C Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:4,997,950-5,028,401 (from NCBI) This gene has 4 transcripts (splice variants), 186 orthologues, 41 paralogues and is associated with 2 phenotypes. Ubiquitous expression in heart (RPKM 51.8), fat (RPKM 28.5) and 24 other tissues. Summary Web13 nov. 2001 · A new study has found that polymorphisms in the host gene kif1C, which encodes a kinesin-like motor protein, determine whether mouse macrophages are …

WebKif1C codes for a transport protein related to kinesins, which are known to carry molecular cargo along cellular highways, called microtubules. Dietrich speculates that the …

WebLe gène kif1C a présenté quatre formes de variants, deux entraînant la résistance et deux entraînant une susceptibilité au germe de l’anthrax. La protéine codée par Kif1C est … boufrayWebYosuke Tanaka works at The University of Tokyo, Tokyo, Japan Department and is well known for Nodal Flow, Retinoic Acid and Kinesin Superfamily Proteins. bouftang st leuWebDOI: 10.1016/S0960-9822(01)00476-6 Corpus ID: 16408765; Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor @article{Watters2001Kif1CAK, title={Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor}, author={James W. Watters and Ken … bouftangWebThese antibodies target KIF1C in Human, Mouse and Rat samples. Our KIF1C polyclonal antibodies are developed in Rabbit. Find the KIF1C antibody that fits your needs. … bouf tardKinesin-like protein KIF1C is a protein that in humans is encoded by the KIF1C gene. Kif1C is a fast, plus-end directed microtubule motor. It takes processive 8nm steps along microtubules and can generate forces of up to 5 pN. Kif1C transports α5β1-integrins in human cells. Kif1C has been shown to be non … Meer weergeven KIF1C has been shown to interact with PTPN21 and YWHAG. KIF1C is a dimeric molecule that is held in an autoinhibited state by interaction of its stalk with the microtubule binding interface of the motor domain. … Meer weergeven • Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, et al. (June 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" Meer weergeven • Overview of all the structural information available in the PDB for UniProt: O43896 (Kinesin-like protein KIF1C) at the PDBe-KB. Meer weergeven bouftassWebKif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor. Watters JW et al. Current Biology. 2001 Oct 02; 11(19):1503-1511 bouftonmouthWebFinally, the susceptibility of certain inbred mice to anthrax lethal toxin was associated with mutations in the kinesin-like protein Kif1C, a discovery that could help to explain how … bouftou chatain