MyoD, also known as myoblast determination protein 1, is a protein in animals that plays a major role in regulating muscle differentiation. MyoD, which was discovered in the laboratory of Harold M. Weintraub, belongs to a family of proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix … See more MyoD was cloned by a functional assay for muscle formation reported in Cell in 1987 by Davis, Weintraub, and Lassar. It was first described as a nuclear phosphoprotein in 1988 by Tapscott, Davis, Thayer, … See more MyoD is a transcription factor and can also direct chromatin remodelling through binding to a DNA motif known as the E-box. MyoD is known to have binding interactions with … See more IFRD1 is a positive cofactor of MyoD, as it cooperates with MyoD at inducing the transcriptional activity of MEF2C (by displacing HDAC4 from MEF2C); moreover IFRD1 also … See more • MyoD+Protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural information available in the PDB for UniProt: P10085 (Mouse … See more The function of MyoD in development is to commit mesoderm cells to a skeletal myoblast lineage, and then to regulate that continued state. MyoD may also regulate muscle repair. MyoD See more Wnt signalling from adjacent tissues has been shown to induce cells in somites that receive these Wnt signals to express Pax3 and Pax7 in addition to myogenic regulatory factors, including Myf5 and MyoD. Specifically, Wnt3a can directly induce MyoD expression via See more MyoD has been shown to interact with: • C-jun, • CREB-binding protein, • CSRP3, See more WebNX_P15172 - MYOD1 - Myoblast determination protein 1 - Function. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into …

Pharos : Target Details - MYOD1

WebApr 8, 2024 · Summary Myoblast determination protein 1 (MyoD) dynamics define the activation status of muscle stem cells (MuSCs), aiding in muscle tissue regeneration after injury. However, the lack of experimental platforms to monitor MyoD dynamics in vitro and in vivo has hampered the investigation of fate determination and heterogeneity of MuSCs. Webmyoblast: [noun] an undifferentiated cell capable of giving rise to muscle cells. population of western region of ghana

Detection of satellite cells during skeletal muscle wound …

WebOct 14, 2008 · Protein names Recommended name Myoblast determination protein 1 Alternative names Class C basic helix-loop-helix protein 1 ( bHLHc1) Myogenic factor 3 ( … WebPAX3 and PAX7 encode proteins crucial for myoblastic development embryologically. FKHR is a member of the fork head family of transcription factors. These fusion proteins have … WebFeb 3, 2024 · Interestingly, the muscle transcription factor myoblast determination protein 1 (MyoD1) is significantly repressed in TAZ-KO cells and TAZ-KO mouse hearts. Exogenous expression of MyoD1 rescued the myogenesis defects previously observed in TAZ-KO cells. Our data suggest that MyoD1 repression is caused by upregulation of the MyoD1 negative ... population of west glacier montana